Primetime Emmy Award for Outstanding Lead Actress in a Drama Series 2022

74th Primetime Emmy Awards · held September 12, 2022 · 6 nominees

• Winner Zendaya · Euphoria
• Nominee Sandra Oh · Killing Eve
• Nominee Jodie Comer · Killing Eve
• Nominee Laura Linney · Ozark
• Nominee Reese Witherspoon · The Morning Show
• Nominee Melanie Lynskey · Yellowjackets

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